Manipulators

Narishige have a reputation for manufacturing high quality manipulation equipment used in many fields. We supply the full range of Narishige coarse and fine manipulators for electrophysiology and injection.

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Injection System Manipulators
Injection System Manipulators
At Digitimer we have an extensive range of Injection Manipulators. Injection Manipulators can be used for various experimental applications and our selection includes both high and low variations for you can find something to suit your exact needs.
Subcategories / Products
B-8B B-8C Ball Joints
IP Iron Plate
GJ 1 Magnetic Stand
MN 153 Micromanipulator
M 152 Manipulator
MN 151 Joystick Micromanipulator
P-1A & P1-B Height Adjustment Plates
MMO 220A Single-axis Oil Hydraulic Micromanipulator
MMO 203 Three-axis Oil Hydraulic Micromanipulator
Electrophysiology System Manipulators
Electrophysiology System Manipulators
As trusted, leading suppliers of the complete electrophysiology system range from Narishige, we can assist you with ordering mechanical, hydraulic, and motorised manipulators for a variety of electrophysiological applications, such as extracellular field potential recording and patch clamp. Likewise, with an extensive selection of accessories, including microscope and amplifier headstage mounting adaptors, we are sure to have a product that exactly meets your requirements in terms of precision and movement range. Browse our full online range and, if you are ready to order or have any questions, please don’t hesitate to get in touch with the Digitimer team today.
What is electrophysiology?
Electrophysiology is the measurement of current or voltage from electrically active cells within living organisms, from muscle cells to neurons. This measurement can occur at a single-cell or ion channel level, or be the result of simultaneous activity in hundreds or thousands of cells. Electrophysiological techniques provide a unique insight into the workings of ion channels and systems within living organisms. Ultimately, this research can be applied to human studies, leading to improved diagnosis and treatment – giving patients better outcomes. To measure low amplitude cellular currents or voltages, electrophysiologists require highly sensitive equipment to provide precise and reliable control in a range of applications – instruments include electrophysiology system manipulators or micromanipulators and a wide selection of complementary accessories.
Why use electrophysiology system manipulators?
Electrophysiologists use electrophysiology system manipulators or micromanipulators to move very small instruments or tools in experiments conducted under microscopic visualisation. While these-highly trained professionals have exceptional fine motor skills, using purpose-designed devices to complete these delicate positioning and movement tasks is much more effective, as it removes the limitations which pure manual control would impose. Each micromanipulator translates macroscopic movements of the human hand into microscopic movements of the tools, micropipettes and microelectrodes, critically needed for successful electrophysiological recordings..
Functions and applications of electrophysiology system manipulators
Micromanipulators and their accessories allow electrophysiologists to complete a variety of experiments and tasks, including but not limited to:
- Making electrical recordings with micropipettes from single-living cells or preparations, such as brain slices
- Manipulating electrical stimulation electrodes
- Holding perfusion pipettes for the localised application of pharmacological compounds
- Dissecting tissue or single-cell structures
- Completing acute or chronic stereotaxic experiments
The types of electrophysiology system manipulators
Electrophysiology system manipulators generally use three different drive mechanisms – which control their movements. These are either mechanical, hydraulic, or motorised/electronic, each having advantages or disadvantages in certain settings. As well as selecting an appropriate drive mechanism for a micromanipulator, scientists will need to decide between the capabilities of each electrophysiology manipulator. Typically the most important features include:
- The type of movement – coarse or fine movement control, or both
- The direction of movement – be that in single and three-axis manipulators
- The movement range - typically manipulators with fine movement have more restricted overall ranges
The products offered by Narishige should allow every laboratory to select the most suitable electrophysiology system manipulators for their needs without compromising in terms of the precision or reproducibility.
Mechanical
Mechanical micromanipulators use mechanical gears or cantilevers to reduce macroscopic movement into microscopic ones. It should be noted that mechanical drive mechanisms may not be suited to projects that include higher magnification as the micromanipulator can vibrate the instrument when dials are turned.
Motorised or electronic
Motor-driven micromanipulators also use similar gears to mechanical models but are driven by electrical motors that are controlled by remote buttons or joysticks, reducing the risk of vibration.
Hydraulic
Hydraulic micromanipulators may incorporate some mechanical elements but for the most part, use the movement of hydraulic fluid and like their motorised equivalents allow for remote control. Hydraulic manipulators are completely free of electrical interference, which can be a consideration in some applications. Macroscopic movements are scaled down to a microscopic level as the fluid is transferred between cylinders or pistons of larger or smaller diameters. If you need an electrophysiology system manipulator requiring improved instrument stability – as in patch-clamp recordings with motionless micropipettes – consider a water hydraulic model. Alternatively, an oil hydraulic micromanipulator is considered best for fast, quick movements, especially when in conjunction with a joystick controller.
Looking to buy electrophysiology system manipulators?
Our electrophysiology system manipulators are not currently available for online purchase. Due to the complex nature of these devices, we ask all potential customers to first make an enquiry or request a quote, so we can discuss specifics and any microscope mounting adaptor requirements. To do this, you can complete our online quote form, give us a call at +44 (0)1707 328347, or send an email to [email protected]. Once we have received your enquiry, a member of the team will get back to you with further product specifications – including specific application recommendations, tailored advice on the best stimulator for your requirements, and the estimated cost of your requested equipment. If you then wish to go ahead with the purchase, you can submit a purchase order at a time that is convenient to you.
Subcategories / Products
B-9 Ball Joint
AP-12L AP-12N Patch Clamp Headstage Holders
GJD 1 Magnetic Bridge Stand
P-1A & P-1B Height Adjustment Plates
Electrode Holders and Pipette Holders
GJ 12 Magnetic Stand - Thin-type
MX 4 Micromanipulator
MX 2 Micromanipulator
MO 8HL Long Holder for MO 10
MO 10 One-axis Oil Hydraulic Micromanipulator
MP 2 Tilting Micromanipulator
M 3333 Micromanipulator
MM 3 Micromanipulator
MWS 32 Micromanipulator (One-axis Water Hydraulic, Magnet-mount)
UST-3A Joint Attachment
NMN 25 Micromanipulator
UST-3 Solid Universal Joint
UST-2 Solid Universal Joint
NR-12 Rotating Adjustable Clamp
NMN-A Tilting Stand
NMN-21 Micromanipulator
MMN-1 Coarse Manipulator
MHW-103 Three Axis Water Hydraulic Micromanipulator
MHW-3 Three Axis Water Hydraulic Micromanipulator
WR-6 Three-axis Water Hydraulic Micromanipulator
B-9 Ball Joint
UST-1 Solid Universal Joint
NR-35 Rotating Adjustable Clamp
MHW-A Tilting Adaptor
MHW-4 Single Axis Water Hydraulic Micromanipulator
YOU Compact Manipulators
YOU Compact Manipulators
The Narishige YOU series provide a range of compact and budget-friendly manipulators that give precision and reliabilty in an affordable package. Available as complete manipulator sets or as modular components parts, allowing you to assemble your own custom manipulator, the YOU range offers a versatile solution for manipulation in a variety of situations.
Subcategories / Products
UPN-J Holder Joint
UPN-B Ball Joint
UPN-20 Pipette Holder
UPN-10 Pipette Holder
UPN-C Pipette Holder
UPN 1 Pipette Holder
U 1C One Axis Compact Manipulator
U 3C Compact Manipulator
YOU Standard Series Pipette Holders
UM-1PFC Manipulator
UM-1FC Manipulator
UM 3C & UMM 3C Manipulators
UMM 3FC Micromanipulator
YOU 3 Manipulator Set
YOU 2 Manipulator Set
Chronic Manipulators
Chronic Manipulators
Narishige's range of manipulators for chronic electrophysiological recording within the brain are available with a wide range of specifications for animals of different sizes and species. Most feature coarse XY controls with fine and coarse control in the Z axis, allowing electrodes to be precisely targeted on the region of interest.
Subcategories / Products
MD-DCE-7 Connecting Cable 7m (for MD system)
MD-OH-1 Compact Controller
MDO-974A Oil Hydraulic-Motorized Hybrid Micromanipulator (with Open Chamber)
MDO-974 Oil Hydraulic-Motorized Hybrid Micromanipulator (with Closed Chamber)
DM-OH-2 Compact Controller (for DM System)
MO-96A Oil Hydraulic Micromanipulator
MO-97 Oil Hydraulic Micromanipulator
Stereotaxic System Manipulators
Stereotaxic System Manipulators
Narishige have a deserved reputation for designing and manufacturing high quality precision instruments and their stereotaxic equipment demonstrates this superbly. Narishige produce stereotaxic frames, manipulators and accessory instruments suitable for use with mice, rats, new born rats and common marmosets.
Subcategories / Products
IMS-30 Motorized Stereotaxic Microinjector
IMS-20 Motorized Stereotaxic Microinjector
IMS-20 Motorized Stereotaxic Microinjector
SMM-200C Stereotaxic Micromanipulator
SMM-100C Stereotaxic Micromanipulator
MD-DCE-7 Connecting Cable 7m (for MD system)
MD-OH-1 Compact Controller
MDO-84 One-axis Oil Hydraulic-Motorized Hybrid Micromanipulator
MDS-1 One-axis Motorized Stereotaxic Micromanipulator
EB-6 Ear Bars (for Mice)
MA-2 Micromanipulator Stand
MA-1 Electrode Position Calibrator
SHC-1 Cannula Holder
DM-OH-2 Compact Controller (for DM System)
DM-OR1-2 Drum Controller (for DM System)
IMS-3 Stereotaxic Microinjector
IMS-20F Footswitch
IMS-20 Motorized Stereotaxic Microinjector
SM-25HE Multiuse Holder
SM-25C Stereotaxic Micromanipulator (Thin-type, One-axis, Oil Hydraulic System)
SM-25A Stereotaxic Micromanipulator (Thin-type, Coarse/Fine Drive)
SM-11A Attachment
SM-11-HT Stereotaxic Micromanipulator
SM-11 Stereotaxic Micromanipulator
SM-15M-2 Substage
SM-15HE Multiuse Holder
SM-15C Attachment
SM-15B Holder Attachment
SM-15A-2 Attachment
SM-15R-L Stereotaxic Micromanipulator
SMM-A Attachment
SMM-HE Multiuse Holder
SMM-HD Multiuse Holder
SMM-HC Cannula Holder
SMM-HB Holder for Neural Probes
SMM-HA Holder for Neural Probes
SMM-200 Stereotaxic Micromanipulator
SMM-100 Stereotaxic Micromanipulator
SR-A Plate
SR-6B Base Plate
SR-5B Base Plate
CA-6 Head Holding Adaptor (for Common Marmosets)
SR-AC Head Holding Device (for Common Marmosets)
SR-6C-HT Stereotaxic Instruments (for Common Marmosets)
SR-5C-HT Stereotaxic Instruments (for Common Marmosets)
SRS-A Compact Head Holding Device (for Mice/Newborn Rats)
SGP-3 Head Holder (for Rats)
SG-3N Head Holder (for Rats)
SGM-3 Head Holder (for Rats)
CFR-2 Chamber Frame (for Rats)
CFR-1 Chamber Frame (for Rats)
SR-10AR Head Holding Device (for Chronic Experiments on Rats)
SR-10R-HT Stereotaxic Instruments (for Chronic Experiments on Rats)
STS-B Compact Spinal Cord Clamps (for Rats)
ST-7R-HT Stereotaxic Instruments with Spinal Cord Clamps
SRP-5R-HT2 Stereotaxic Instruments (for Rats/MRI-compatible)
SRP-AR2 Head Holding Device (for Rats/MRI-compatible)
EB-4N Auxiliary Ear Bar (for Rats)
EB-3A Ear Bars (for Rats)
RA-6N Head Holding Adaptor (for Rats)
GM-3 Anesthetic Mask (for Rats)
SR-AR Head Holding Device (for Rats)
SR-6R-HT Stereotaxic Instruments (for Rats)
SR-5R-HT Stereotaxic Instruments (for Rats)
SGP-4 Head Holder (for Mice)
SGM-4 Head Holder (for Mice)
MAG-3 Head Holding Device (with Angle Adjuster / for Mice)
MAG-2 Head Holding Device (with Angle Adjuster / for Mice)
MAG-1 Simple Head Holder Plate (for Mice)
CP-2 Chamber Plate (for Mice)
CP-1 Chamber Plate (for Mice)
CP Chamber Plate (for Mice)
CF-10 Chamber Frame (for Mice)
SR-9AM Head Holding Device (for Chronic Experiments on Mice)
SR-9M-HT Stereotaxic Instruments (for Chronic Experiments on Mice)
STS-A Compact Spinal Cord Clamps (for Mice/Newborn Rats)
ST-7M-HT Stereotaxic Instruments with Spinal Cord Clamps
EB-5N Auxiliary Ear Bar (for Mice)
SRP-AM2 Head Holding Device (for Mice/MRI-compatible)
EB-3B Ear Bars (for Mice)
MA-6N/MA-6N1 Head Holding Adaptor (for Mice)
GM-4 Anesthetic Mask (for Mice)
SR-AM Head Holding Device (for Mice)
SR-6M-HT/SR-6M1-HT Stereotaxic Instruments (for Mice)
SR-5M-HT/SR-5M1-HT Stereotaxic Instruments (for Mice)
BE 8 Manipulator with Ball Joint
Manipulator Microscope Adaptors
Subcategories / Products
Manipulator Microscope Adaptors for Injection
Manipulator Microscope Adaptors for Electrophysiology
Manipulator Accessories & Consumables
Manipulator Accessories & Consumables
Subcategories / Products
TSG-4 Double Magnetic Stand
TSP-6 Mounting Plate
TSG-3 Double Magnetic Stand
TSG-2 Double Magnetic Stand
IP Iron Plate
GJ 1 Magnetic Stand
P-1A & P1-B Height Adjustment Plates
GJD 1 Magnetic Bridge Stand
X 4 Rotating X Block
GJ 8 Magnetic Stand

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