The new D360R Multi-channel Isolated Research Amplifiers are intended for electroencephalography (EEG), electromyography (EMG) or evoked potential (EP) studies in a human research environment. Based on the design of our extremely popular 8-channel D360 Isolated Patient Amplifier, the new D360R-4 is the first of this new family of amplifiers and provides a compact, cost-effective, but highly-specified 4-channel research equivalent. Two channel (D360R-2) and 8-channel (D360R-8) variants of the D360R are being planned for future development.
The four channel D360R-4 has been designed to meet all of the electrical requirements of the medical electrical standard IEC 60601-1, including but not limited to:-
(i) full electrical isolation of the input circuit
(ii) meeting of or exceeding creepage and clearance minimum requirements
(iii) ensuring inputs are single fault condition safe.
Unlike the 8-channel D360, the D360R-4 is NOT a medical device and its use is limited to animal or human research applications.
The D360R-4 comprises a main amplifier unit, a remote pre-amplifier headstage with 4 pairs of differential inputs (plus Common) and dedicated Windows-compatible Client Software. The software provides a virtual front panel for the adjustment of settings, including low-pass and high-pass filters as well as amplifier gain. The pre-amplifier headstage is attached to the main amplifier via a fully detachable 2m long cable, which is easily replaced if it becomes damaged during use.
The D360R-4 provides software and hardware de-block capabilities which can be useful to settle the amplifier inputs following electrode placement or re-positioning. In addition, a TTL controlled de-block function allows a precisely timed external de-block to be applied in situations where a large stimulation artifact might obscure a short latency response.
Analogue signal outputs mean that the D360R-4 is fully compatible with a vast array of commercially available data acquisition systems. As a result, the user can opt to employ their favoured data acquisition and analysis software. Signal outputs are available on the rear panel via a 9-way “D” connector. The D360R-4 is supplied with a “D” to multi-BNC cable for connection to BNC-based data acquisition systems.
The D360R-4 supports system expansion as multiple D360R-4 amplifiers can be connected to a single computer (via several USB sockets or hub) to allow multiples of 4 channels to be controlled through a single software interface.
I understand the D360R amplifiers, including the D360R-4, are based on the 8 Channel D360, other than the number of channels, how do they differ?
The D360 is certified to the European Medical Device Directive and is suitable for patient use, while the D360R-4 is designed for safe use in human research, but is not a medical device. The D360 incorporates electrode impedance checking via the control software and headstage LEDs; the D360R-4 does not have any electrode impedance checking mode. The D360 allows for internal linking of +ve or -ve electrode inputs, so multiple channels can share a single reference electrode. The D360R-4 operates in standard differential mode with an additional Common input. The D360 software allows for multiple groups of channels. The D360R-4 allows channels to be linked and share settings, but does not permit multiple channel grouping.
The D360 is not compatible with the 64bit versions of CED Signal and Spike2 software, will the D360R family be compatible with them?
Yes, the D360R software has been written in order to ensure it is fully compatible with other 64bit software like CED Spike2 and Signal.
I am looking for an amplifier suitable for recording motor evoked potentials (MEPs) generated by transcranial magnetic stimulation (TMS), is the D360R-4 a good choice?
Absolutely. Just like the original D360, the D360R-4 has been designed for full compatibility with TMS and electrical stimulation methodologies, providing a low noise amplifier with excellent common mode characteristics, in order to minimise stimulus artefacts.
I see the cable between the headstage preamplifier and the main unit appears to be removable. Is it possible to replace this if it become damaged or even purchase alternative lengths?
We know that headstage cables can receive quite a lot of abuse in a busy laboratory environment and they will on occasions suffer from damage. For the D360, cable replacement was a costly and time consuming process, as it required the headstage to be returned to Digitimer for rewiring. With the D360R family, we have opted to use a fully removable cable which we will be able to supply replacements for and possibly in a range of lengths.
Is it possible to use multiple D360R on a single host computer as an 8, 12 or 16 channel EMG system?
Yes, multiple D360R-4 amplifiers can be connected to a single host computer to allow for the configuration of systems with greater than 4 channels. The settings for each amplifier will be vertically arranged in a single instance of the D360R control software.
- Operator’s manual
- D360R-4 Control Software (on USB flash drive)
- D-USBF – USB cable
- Headstage connection cable
- D360R-4 Signal output lead
- Mains (power) lead
- Electrodes and accessories