Digitimer represents Alpha MED Science Inc. and offers a range of multielectrode array (MEA) systems.

Developed from the Panasonic MED64 system, Alpha MED now manufactures the most sensitive in vitro MEA systems available for extracellular electrophysiology or electrophysiological studies looking to understand electrically active cells, including iPSC derived neurons or cardiomyocytes and neuronal networks in brain slices.

Alpha MED’s multielectrode arrays feature up to 64 microelectrodes, each able to detect cellular activity and serve as an interface between biological activity and electronic amplification technology.  Low amplitude signals are amplified and can be acquired and analysed using dedicated MED64 software.

Benefits of the MED64 multi-electrode array systems:

  • Increased sensitivity – the MED64 multi-electrode array systems are the most sensitive in the market, in terms of signal to noise ratio, for in vitro extracellular MEA recording.
  • Low electrode impedance – by increasing the surface area by x100-200 times, electrode impedance is reduced and performance is improved, ensuring the lowest amplitude signals are not lost in background noise.
  • Fast and easy set-up – research laboratories can expect to be recording data from cultures after just a few hours.

Explore the benefits of the MED64 multi-electrode array system in more detail.

The most sensitive multi-electrode array – available from Digitimer

MED64 systems are configured according to your needs, so purchasing from our MEA range is possible once a bespoke quote has been created. If you are interested in embarking on MEA recordings, please enquire today or request a quote, giving us some basic information about your specific experimental aims and the cell or tissue types you would plan to use.

This will allow us to make appropriate suggestions for your project, help you with your funding bid and hopefully guide you towards a future purchase.

To get in touch, you can complete our online quote form, call 01707 328347, or send an email to [email protected] and we’ll get back to you as soon as we can.

Frequently Asked Questions

While both a multi-electrode array (MEA) and an electroencephalogram (EEG) can measure electrical activity from neural tissue, they differ in scale, application, and how they can be used. 

  • Scale 

EEG covers the whole living brain, while MEA provides information relating to small neural networks within regions of the brain.

  • Application 

EEG can diagnose major conditions including epilepsy or sleep disorders while MEA is used for toxicology, pharmacology, neuroscience or cardiac research, possibly including studies of epilepsy or investigating how neurodegenerative diseases develop.

  • How they are used 

EEG is conducted via electrodes on the scalp of the patient while MEA uses embedded electrodes that are in contact with a tissue sample or cells within a specially designed chamber (probe).

For more information about the different applications for multi-electrode array systems, why not speak to the Digitimer team? 

Each standard MED64 system includes a main amplifier and preamplifier, but it is the choice of probe connectors and probes that really allow you to target specific experiments and aims.  Systems can be configured according to the preparation, the number of electrodes needed per sample and any perfusion or electrical stimulation requirements.

As a recent MED64 installation at University College London demonstrates, time spent considering how MEA technology might be used in the future can enhance the capability of a system within its lifetime. The MED64 MEA is ideal for use in a range of electrophysiological studies, including but not limited to:

  • Recording spontaneous activity from hiPSC-derived neuronal cells upon differentiation and maturity
  • Examining cell cultures for disease modelling such as epilepsy, prion disease, and other neurodegenerative disorders
  • Drug screening or neurotoxicology studies
  • Documenting functional maturity of cardiomyocytes 

For a bespoke quote for your next project, call us on 01707 328347 or email us at [email protected] and we’ll get back to you with a brochure.

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