Research and Clinical Instruments Manufacturer & Supplier
Acquisition InterfacesNational Instruments USB-6341-BNCHEKA LIH 8+8 Data Acquisition SystemAmplifiersNeuroLog SystemD360 8-Ch. EP/EEG/EMGD360R 4 Channel Isolated Research Amplifier/FilterD440 2/4 Ch. EMG/EPHEKA EPC10 Patch ClampHEKA EPC10 2/3/4 Ch. Patch ClampHEKA EPC800 Patch ClampAnti-vibration SystemsThorLabs Science DesksNarishige ITS Anti-vibrationNarishige Double MagnetNarishige SBP-2 BaseplateCell InjectorsPLI-100A Pico-injectorPLI-90A Pico-injectorNarishige IM-11-2Narishige IMS-20Narishige IM-21Narishige IM-400Injection Accessories
Incubators & ChambersAutomate Perfusion ChambersMedical Systems MicroincubatorsSSD Brain Slice KeepersSSD Brain Slice ChambersIontophoretic DevicesD380 Dye MarkerMains Noise EliminatorsHumBug Noise EliminatorD400 2/4Ch. Mains Noise EliminatorManipulatorsElectrophysiology System ManipulatorsInjection System ManipulatorsStereotaxic Manipulators“YOU” Compact ManipulatorsChronic ManipulatorsAccessoriesMicroscope Adaptors (Ephys)Microscope Adaptors (Injection)
MEA SystemsMED64 – BasicMED64 – Quad IIMED64 – AllegroMED64 – Plex 4/8MED64 – PrestoMED64 – Mobius SoftwareMED64 ProbesPerfusion EquipmentPerfusion SystemsPerfusion AccessoriesPipette FabricationMicropipette PullersMicroforges & MicrogrindersReplacement PartsCapillary GlassProgrammers & TimersDG2A Train Delay GeneratorNeuroLog System
Signal GeneratorsTG315 Function GeneratorSoftwareQtracW Threshold TrackingQTMS QtracW TMS ExtensionAutoMate EasycodeHEKA Chartmaster SoftwareHEKA Patchmaster SoftwareHEKA Fitmaster SoftwareStimulatorsDS2A Constant VoltageDS3 Constant CurrentDS4 Biphasic Constant CurrentDS5 Bipolar Constant CurrentDS7A/DS7AH Constant CurrentDS7R Constant Current ResearchDS8R Biphasic ResearchD121-11 Mounting FrameD185 Transcranial MultiPulseD330 MultiStim SystemNL800A Current Stimulus Isolator
A/D Interface ModulesNL201 – Spike TriggerNL601 – Pulse IntegratorAmplifier ModulesNL100AK – HeadstageNL100RK (NL100AKS & NL100C)NL102G – DC PreamplifierNL104A – AC PreamplifierNL106 – AC/DC AmplifierNL108A – Pressure AmplifierNL109 – Bridge AmplifierNL120S – Audio AmplifierNL820A – 4-Ch. IsolatorNL844 – 4-Ch. AC PreamplifierAnalogue ModulesNL254 – RatemeterNL506 – Analogue SwitchNL703 – EMG Integrator
Digital ModulesNL405 – Width/DelayNL501 – Logic GateNL505 – Flip FlopNL603 – CounterNL730 – Pulse ShiftFilter & Conditioner ModulesNL125/6 – Band-Pass FilterNL134/5/6 – 4-Ch. Low Pass FiltersNL143 – 3-Ch. Difference AmplifierNL144 – 4-Ch. High Pass FilterNL530 – Signal ConditionerNL540 – Inverting Attenuator (Alt. Gain)Generator ModulesNL301 – Pulse GeneratorNL304 – Period GeneratorNL412 – Pulse
NeuroLog AccessoriesAccessory KitsAdaptors & Adaptor CablesSockets (for cable mounting)Sockets (for panel mounting)Plugs (for cable mounting)Extension CablesCablesElectrode HoldersMiscellaneous AccessoriesNeuroLog System CasesNL900D – NeuroLog System CaseNL905 – Compact NeuroLog System Case
Pressure Transducers & AccelerometersPressure TransducersForce TransducersAccelerometersStimulator ModulesNL510 – Pulse BufferNL512 – Biphasic BufferNL800A Constant Current Stimulus Isolator
Application NotesSignal AmplificationTriggering & Pulse GenerationSignal Conditioning Filtering & ProcessingElectrical Stimulation
Isolated Amplifiers for EMG/EEG/EP D440 2/4-Ch. EMG AmplifierD360 8-Ch. Patient Amplifier D360R 4-Ch. Research AmplifierAmplifier Accessories D175 Electrode Impedance Meter D179 Performance Checker D360 Audio Interface D360 USB to Serial Adaptor D177 Bio-Feedback Unit
Peripheral Stimulators DS5 Isolated Bipolar Constant Current Stimulator DS7A & DS7AH HV Constant Current Stimulator DS7R HV Constant Current Research Stimulator DS8R Biphasic Constant Current Stimulator
Transcranial Cortical StimulatorsD185 MultiPulse Cortical Electrical StimulatorStimulator AccessoriesD188 Remote Electrode SelectorElectrode Connection HeadboxesTrigger CablesElectrode HandlesMiscellaneous Items
Neurodiagnostic AccessoriesIntraoperative Neuromonitoring (IONM) Electroecephalography (EEG) Electromyography (EMG)Nerve Conduction Study (NCS) Evoked Potential (EP)Axelgaard Stimulation ElectrodesTouch Proof Plugs Adaptors & Electrode Linkers
Cath SecureCATH-SECURE – OriginalCATH-SECURE – ExtendedCATH-SECURE PlusCATH-SECURE – Dual TabCATH-SECURE For KidsNG SECURE
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Urodynamic ConsumablesUrodynamics CathetersPump Infusion SetsTransducer Pressure DomesFemale Voiding AdaptorDuckbill ValvesSetguards3-Way Taps
The D330 MultiStim System, available here at Digitimer, has been designed for use in laboratories where a number of in vitro preparations or cell culture wells need stimulation from a low impedance source. These studies are known as punctate or field/bath stimulation.
The Multistim System uses a common timing waveform for each channel but a different stabilised stimulus to each preparation. The Multistim includes modules for constant voltage stimulation up to 100v 1a (D333H) and constant current stimulation up to 500mA from a 100v source (D343).
The D330 Multistim System is available in a 19” rack or bench mountable case, to suit the individual requirements of our clients and customers, which can house up to 10 channels of stimulation. The system is modular so that a minimal system may be expanded upon at a later date or split into smaller units for two sites.
Modules are available to generate pulses variable in frequency and duration; these can be supplied in bursts using a gating waveform variable in repetition, duration or count. In addition, extra delayed pulses can be generated for studies involving refractory period. Most controls on the D330 Multistim System are either single turn or 10-turn with locking dials. Sockets are fitted to allow external control and synchronisation.
Contact us by calling us on 01707 328347 or by emailing us at email@example.com if you wish to learn more information about the D330 MultiStim System. The experienced, knowledgeable Digitimer team will be able to answer any questions you have to do with our full collection of products.
Do You Need Help with MultiStim System Module Selection?
D330 MultiStim Brochure
D330 MultiStim Operating Modes
D330 MultiStim Module Selection Flowchart
Publications which cite use of the Digitimer D185 can be found on Google Scholar.
Of course, feel free to contact us to discuss your requirements, but perhaps you should take a look at our comprehensive D330 operating mode notes and module selection flowchart (see above) before doing so.
A single D337 rack supports 2 -10 channels of stimulation. In addition, multiple D337 racks can be linked by a “sync” cable allowing this maximum to be increased further. Please remember that for safety reasons any empty bays must have blanking panels fitted to protect the user from possible electric shock.
The output sockets on the MultiStim fit 2mm plugs. We can supply these in packs of 10 with either black or red insulation (part number NL822P/10-Blk or NL822P/10-Red).
This is the simplest possible MultiStim setup. If your software and hardware is capable of producing the required stimulation timing characteristics (i.e pulse frequency and duration), then all you require is a D337 Case, D334B Sync Module, the required number of dual stimulator modules/blanking panels and an appropriate cable (usually Lemo plug to BNC plug) to link the interface to the MultiStim. We also recommend a D335 meter in order to easily monitor the output current.
The D337 Case is specifically designed to hold timing and pulse generator modules in the first (left-hand) four bays. Dual width stimulator modules (D333H or D343) will ONLY operate correctly if they are placed in the remaining 10 bays.
The D333H and D343 modules include an overload LED which serves to warn the user if the current requested or required cannot be supplied by the stimulator. The D333H modules have an upper limit of 1A, so if the impedance of the preparation and the voltage settings are high enough, the module will reach the maximum output current and indicate an overload. The same effect can be seen with the D343 except this is a constant current device and will supply up to 500mA until it reaches a compliance limit of 100V. If you run into the above problems, consider whether you need to have the output settings so high and also check that your preparation and electrodes provide a low impedance connection.
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