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Pressure Transducers & AccelerometersPressure TransducersForce TransducersAccelerometersStimulator ModulesNL510 – Pulse BufferNL512 – Biphasic BufferNL800A Constant Current Stimulus IsolatorNeurolog System Application NotesSignal AmplificationTriggering & Pulse GenerationSignal Conditioning Filtering & ProcessingElectrical Stimulation
Amplifier Accessories D175 Electrode Impedance Meter D179 Performance Checker D360 Audio Interface D360 USB to Serial Adaptor D177 Bio-Feedback Unit Isolated Amplifiers for EMG / EEG D440 2 or 4 Channel Isolated Amplifier D360 8-Channel Patient Amplifier D360R 4 Channel Research Amplifier
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Peripheral Stimulators DS5 Isolated Bipolar Constant Current Stimulator DS7A & DS7AH HV Constant Current Stimulator NEW DS7R HV Constant Current Research Stimulator NEW DS8R Biphasic Constant Current Stimulator
Stimulator AccessoriesD188 Remote Electrode SelectorElectrode Connection HeadboxesTrigger CablesElectrode HandlesMiscellaneous ItemsTranscranial Cortical StimulatorsD185 MultiPulse Cortical Electrical Stimulator
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Urodynamic ConsumablesUrodynamics CathetersPump Infusion SetsTransducer Pressure DomesUrodynamic Consumables Accessories
Continuing the tradition of providing the world’s best electrophysiology amplifiers, the HEKA EPC10n USB Patch Clamp Amplifier Double, Triple, and Quadro are the optimal instruments for performing double or triple patch experiments. Although either two (EPC 10 USB Double), three (EPC 10 USB Triple) or four (EPC 10 USB Quadro) amplifiers are combined in a single housing; each amplifier is completely independent with clearly defined operation and handling. HEKA’s software stimulates the desired amplifier and selected channels are programmed without tedious connection of cables by the user.
The amplifiers and headstages are clearly identified, thus, the user can immediately assign the amplifiers to particular patched cells. Although independent, the amplifiers can be stimulated simultaneously with resulting simultaneous data acquisition. Current or voltage signals from multiple amplifiers can be recorded, displayed and even analyzed online. This versatility makes these amplifiers ideal instruments for experiments such as studying gap junction potentials, pre- and post-synaptic events, and usage in amperometric measurements.
The versatility of the HEKA EPC10n USB Patch Clamp Amplifier Double and HEKA EPC10n USB Patch Clamp Amplifier Triple stem from their adjustment and control at the software level. Leak currents, capacitances, and series resistances can instantly be neutralized automatically while you still retain the possibility of full manual control of the amplifier. Voltage- and Current-Clamp experimental protocols are easily automated; not only ensuring simplicity, great speed and accuracy but also providing enormous flexibility for the integration of extensions such as photometric and fluorescence measurements.
The EPC 10 USB Double and EPC 10 USB Triple also provide economical solutions in comparison with the combination of several individual instruments. They also have the advantages of optimized noise performance and grounding over that of multiple external amplifiers.
The design of the pre-amplifier allows “True current clamp” experiments to be performed. In current clamp (CClamp) mode, the headstage acts as a voltage follower circuit, which guarantees very fast and accurate membrane potential recordings.
The Low Frequency Voltage Clamp (LFVC) is a modified current clamp mode, that allows for measuring transient potentials, such as action potentials and synaptic potentials, as in the usual current clamp, while the average membrane potential is kept constant at a value chosen by the user.
The slim shape of the headstage allows optimal access to your cells. The connection to the pipette holder is achieved via a stable BNC connector.
Adapter plates for various micromanipulators are available from HEKA.
EPC 10n USB Patch Clamp Amplifier
Pulse & Patchmaster Compatibility Chart
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