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DS5 Isolated Bipolar Constant Current Stimulator


1.  I am interested in purchasing a DS5 stimulator, but I am not sure how I would control it, can you help?
2.  Is it possible to control the settings of the DS5, such as output ranges via remote devices/software?
3.  I see that the DS5 is limited to 50mA, is there the possibility to modify it for a higher output current?
4.  I am currently using the DS5 but have found it difficult to re-enable the output after auto-zeroing and sometimes have to attempt this several times, is there a problem with my stimulator?

5.  I see there is a USB socket on the back of the DS5, what is this for?

6.  What is the minimum interval between stimulation "pulses" using the DS5?
7.  I switched on my DS5 and started using it, but found that the baseline output drifted considerably for the first 30 minutes, even though the voltage input was zero.  Why is this?
8.  I am considering using the DS5 for some studies of rodent nerve excitability.  Is the DS5 suitable for this?

 

1.  I am interested in purchasing a DS5 stimulator, but I am not sure how I would control it, can you help?

The DS5 has been designed to be as versatile as possible and therefore it should be compatible with most D/A hardware and software.  The DS5 merely requires an analogue input of ±1, ±2.5, ±5 or ±10V at the BNC socket on the rear to provide the waveform which describes the stimulus.  However, the user should note that they will need to source or write software that allows them to define the characteristics of the waveform.

  

2.  Is it possible to control the settings of the DS5, such as output ranges via remote devices/software?

At this time, the DS5 is not able to have adjustments made to its setting by any other method than the front panel controls.  We are developing software that will allow this to be possible, but we do not have a release date for this yet.

  

3.  I see that the DS5 is limited to 50mA, is there the possibility to modify it for a higher output current?

No, after taking advice from collaborators we decided that a ±50mA limit was adequate for most cases, however, it is possible to link two DS5's together in parallel to increase the overall stimulus output.

  

4.  I am currently using the DS5 but have found it difficult to re-enable the output after auto-zeroing and sometimes have to attempt this several times, is there a problem with my stimulator?

It is likely that the failure to re-enable the output is accompanied by a warning icon which indicates that re-enabling would result in DC stimulation.  If this is the case, then the cause is almost certainly due to (i) a voltage waveform still being applied at the voltage input during the auto-zeroing procedure or (ii) noise being picked up through the input socket.  For safety reasons, the DS5 will not re-enable if a significant stimulus current would immediately result.

  

5.  I see there is a USB socket on the back of the DS5, what is this for?

This socket served two purposes - (i) It will be utilized to allow the operator to upgrade the firmware of the DS5 in the future and (ii) it will provide the communication link to control the DS5 settings from PC software.  These functions will be implemented at a later date.

6What is the minimum interval between stimulation "pulses" using the DS5?

The DS5 will identify the end point on a stimulation pulse as the stimulus current value falling to within ±400µA for a minimum period of 200µs or a sustained reversal of stimulus polarity (irrespective of the current amplitude).  Therefore if you intend to carry out repetitive stimulation pulses of the same polarity, there needs to be a 200µs gap between them.  If the pulses are of alternating polarity, there is no requirement for an interval (e.g as in a sine wave).

7.  I switched on my DS5 and started using it, but found that the baseline output drifted considerably for the first 30 minutes, even though the voltage input was zero.  Why is this?

As with many electronic instruments, certain components within the DS5 make it important that the stimulator is switched ON and "warmed up" for at least an hour before it is used with a subject.

8.  I am considering using the DS5 for some studies of rodent nerve excitability.  Is the DS5 suitable for this?

The DS5 is designed for use with human nerves in vivo and as such the sort of currents it generates are in the mA range.  Even when the output of the DS5 has been recently autozeroed, some small leak currents (in the µA range) can persist and while these would be insignificant for human studies, they may be unwelcome in the rodent equivalent.  Instead, we would recommend our NEW DS4 stimulator for such non-human research studies.


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