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Combination
inline heater plus multi-channel focal drug delivery.
Maintain bath temperature and
rapid drug wash-out with a high-flow bath line while quickly
switching 4-8 preheated solutions through the Perfusion
Pencil® Steady 37°C at 5 ml/minute flow rates
through both the bath line and tip.
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Advanced
auto-tuning temperature lock
- Fuzzy logic PID
software maintains chamber or reagent temperature to
within 1°C of set point or better. The ThermoClamp
calibrates its own tuning for ideal temperature control
- no need to guess "loop speed" settings.
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Designed
for physiology research
- No metal anywhere in
the flow path - unlike some competitors. Low noise for
electrophysiology with internal and external grounding
plus electrical isolation between liquids and heating
elements.
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Ready
to use - Includes
everything you need for heated perfusion: power supply,
temperature sensors, and inline heater with easy Luer
lock tube connections.
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ThermoClamp™-1
Temperature Control System
You
can have rapid switching, fast wash-out, and accurate temperature
control at the same time. Set the ThermoClamp temperature from
ambient to 50°C. A front-panel BNC provides an analog output of
current temperature for recording. Different sizes of replaceable
tips are interchangeable with our standard Perfusion Pencil. The
tips have microliter dead volume for rapid switching. No messy water
jacket is required, but the separate high-flow line is capable of
heating a perfusion chamber with water jacket if desired.
Do
you need to change your prep's temperature over the course of an
experiment? A programmable "ramp and hold" feature can
automatically vary the set point over time. The ThermoClamp system
includes bath and Perfusion Pencil thermocouple sensors. Automatic
overtemp. and thermocouple failure protection alerts you to any
problems. Incorporate temperature control into your perfusion rig
with simple micromanipulator mounting.
Operation
Connect
multiple reagent tubes from any perfusion system to the heated
Perfusion Pencil on a manipulator directed into your chamber. If
desired, connect a separate buffer line to the "high-flow"
bath Luer connection on the Pencil, and the outflow to your chamber.
If your chamber includes a water jacket, you can use the high-flow
line with a constant flow of water to heat the chamber. Place the
bath thermocouple sensor in the chamber. Set your desired
temperature on the controller and begin liquid flow. The ThermoClamp
will monitor bath temperature and heat the liquids flowing through
the Perfusion Pencil to keep the chamber at exactly the desired
temperature. Your perfusion system can quickly change solutions
through the Perfusion Pencil tip and also deliver buffer for fast
wash-out. Sophisticated circuitry will "auto tune" the
ThermoClamp heating parameters based on your flow rates, chamber,
and tubing to clamp the temperature and minimize over/undershoot.
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