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Several students have conducted PhD research on various aspects of MEPs and made use of the Digitimer D185 MultiPulse Transcranial Cortical Stimulator.  Much of this work has now been published in full and can be accessed via the links below.

L.H. Ubags PhD

  

  

Chapter 1 - General Introduction.


Chapter 2 - Kalkman CJ, Ubags LH, Been HD, Swaan A, Drummond JC;

Improved amplitude of myogenic motor evoked responses after paired transcranial electrical stimulation during sufentanil/nitrous oxide anesthesia.  Anesthesiology 1995 Aug 83:2 270-6.


Chapter 3 - Ubags LH, Kalkman CJ, Been HD, Drummond JC

The use of a circumferential cathode improves amplitude of intraoperative electrical transcranial myogenic motor evoked responses.  Anesth Analg 1996 May 82:5 1011-4.


Chapter 4 - Ubags LH, Kalkman CJ, Been HD, Porsius M, Drummond JC

The use of ketamine or etomidate to supplement sufentanil/N2O anesthesia does not disrupt monitoring of myogenic transcranial motor evoked response monitoring.  J Neurosurg Anesthesiol 1997 Jul 9:3 228-33.


Chapter 5 - Ubags LH, Kalkman CJ, Been HD, Koelman JH, Ongerboer de Visser BW; Presented (in part) at Annual Meeting of the American Society of Anesthesiologists, San Diego, October 1997.

A comparison of electrical and magnetic transcranial stimulation for intraoperative myogenic motor evoked response monitoring.  Part Published:  Anesth Analg. 1999 Mar;88:3 568-72


Chapter 6 - Ubags LH, Kalkman CJ, Been HD, Drummond JC

Differential effects of nitrous oxide and propofol on myogenic transcranial motor evoked responses during sufentanil anesthesia.  British Journal of Anaesthesia 1997 79:590-4.


Chapter 7 - Ubags LH, Kalkman CJ, Been HD

Influence of isoflurane on myogenic motor evoked potentials to single and multiple transcranial stimuli during nitrous oxide / opioid anesthesia.  Neurosurgery 1988 Jul 43:1 90-4.


Chapter 8 - Ubags LH, Kalkman CJ, Tjan DHT, Bateman JJB, Koelman JHTM, Ongerboer de Visser BW; Presented at Annual Meeting of the American Society of Anesthesiologists and the Annual Meeting of the Society for Neurosurgical Anesthesia and Critical Care, New Orleans, 1996.

The influence of clonidine, ketanserin, nitroglycerin and esmolol on myogenic transcranial motor evoked potentials.


Chapter 9 - Ubags LH, Kalkman CJ, Been HD, Porsius M, Bosch DA

Intraoperative spinal cord monitoring with myogenic motor evoked potentials to multiple transcranial electrical stimuli; experiences during 208 operations.


H.P.A. van Dongen PhD

  

  

Chapter 1 - Introduction


Chapter 2 - van Dongen EP, Schepens MA, ter Beck HT and Boezeman EH

The role of evoked potentials in the prevention of spinal cord ischemia during thoracic and thoracoabdominal aortic surgery.  Published in the 4th volume in the course on techniques in vascular surgery: "Thoracic and thoracoabdominal aortic aneurysms" Editors: Chiesa R and Melissano G.


Chapter 3 - van Dongen EP, ter Beck HT, Schepens MA, Morshuis WJ, de Boer A, Aarts LP and Boezeman EH

Within patient variability of lower extremity muscle responses to transcranial electrical stimulation with pulse trains in aortic surgery.  Clin Neurophysiol 1999; 110: 1144-48


Chapter 4 - van Dongen EP, ter Beck HT, Schepens MA, Morshuis WJ, Langemeijer HJ, de Boer A and Boezeman EH

Within patient variability of myogenic motor-evoked potentials to multi-pulse transcranial electrical stimulation during two levels of partial neuromuscular blockade in aortic surgery.  Anesth Analg 1999; 88: 22-7


Chapter 5 - van Dongen EP, ter Beck HT, Schepens MA, Morshuis WJ, Langemeijer HJ and Kalkman CJ

The influence of nitrous oxide to supplement fentanyl/low dose propofol anesthesia on transcranial myogenic motor evoked potentials during thoracic aortic surgery.  J Cardiothorac Vasc Anesth 1999; 13: 30-4


Chapter 6 - van Dongen EP, ter Beck HT, Schepens MA, Morshuis WJ, de Boer A, Aarts LP and Boezeman EH

The effect of nitrous oxide on myogenic motor potentials evoked by a six pulse train of transcranial electrical stimuli; a possible monitor for aortic surgery.  Br J Anaesth 1999; 82: 323-8


Chapter 7 - van Dongen EP, ter Beck HT, Aarts LP, Schepens MA, Morshuis WJ, Benning FJ, de Boer A and Boezeman EH

The effect of two low-dose propofol infusions on the relationship between six pulse transcranial electrical stimulation and evoked lower extremity muscle response.  Acta Anaesthesiol Scand 2000 Aug;44(7):799-803


Chapter 8 - van Dongen EP, ter Beck HT, Boezeman EH, Schepens MA, Langemeijer HJ and Aarts LP

Normal serum of S-100 protein and changes in cerebrospinal fluid concentrations of S-100 concentrations protein during and thoracoabdominal aortic aneurysm surgery: Is S-100 protein a biochemical marker of after clinical value in spinal cord ischemia?  J Vasc Surg 1998; 27: 344-6


Chapter 9 - van Dongen EP, ter Beek HT, Schepens MA, Morshuis WJ, Haas FJ, de Boer A, Boezeman EH, Aarts LP

The relationship between evoked potentials and measurements of S-100 protein in cerebrospinal fluid during and after thoracoabdominal aortic aneurysm surgery.  J Vasc Surg 1999 Aug;30(2):293-300


Chapter 10 - van Dongen EP, ter Beck HT, Aarts LP, Schepens MA, Morshuis WJ, de Boer A and Boezeman EH

The impact of monitoring myogenic transcranial motor-evoked potentials during surgical procedures on the descending thoracic and thoracoabdominal aorta.  Part Published:  Ann Thorac Surg 1999 Jun;67(6):1963-7; discussion 1979-80


Chapter 11 - van Dongen EP

Summary and conclusions.


S. Meylaerts PhD

  

  

Chapter 1

Meylaerts SA

Introduction - Spinal Cord Protection during thoracoabdominal aortic aneurysm repair.


Chapter 2

Meylaerts SA, de Haan P, Kalkman CJ, Lips J, de Mol BA and Jacobs MJ

The influence of regional spinal cord hypothermia on transcranial myogenic motor-evoked potentials and the efficacy of spinal cord ischemia detection.  Journal of Thoracic & Cardiovascular Surgery 118(6):1038-1045, 1999.


Chapter 3

Meylaerts SA, Kalkman CJ, de Haan P, Porsius M, Jacobs MJ.

Epidural versus subdural spinal cord cooling: cerebrospinal fluid temperature and pressure changes.  Ann Thorac Surg. 2000 Jul;70(1):222-7; discussion 228


Chapter 4

Meylaerts SA, de Haan P, Kalkman CJ, Jaspers J and Jacobs MJ.

Selective segmental artery perfusion during aortic cross-clamping preserves spinal cord neurophysiologic function in pigs.  Part Published with Chapter 5:  Ann Thorac Surg. 1999 Oct;68(4):1278-84


Chapter 5

Meylaerts SA, de Haan P, Kalkman CJ, Jaspers J, Vanicky, I and Jacobs MJ.

Selective segmental artery perfusion during aortic cross-clamping prevents paraplegia in pigs.  Part Published with Chapter 4: J Vasc Surg. 2000 Jul;32(1):160-70


Chapter 6

Jacobs MJ, Meylaerts SA, de Haan P, de Mol BA and Kalkman CJ.

Strategies to prevent neurologic deficit based on motor-evoked potentials in type I and II thoracoabdominal aortic aneurysm repair.  Journal of Vascular Surgery 29(1):48-57, 1999.


Chapter 7

Meylaerts SA, Jacobs MJ, Iterson van V, de Haan P and Kalkman CJ

Comparison of transcranial motor evoked potentials and somatosensory evoked potentials during thoracoabdominal aortic aneurysm repair.  Annals of Surgery 230(6):742-749, 1999.


Chapter 8

Meylaerts SA

General discussion and concluding remarks.


Chapter 9

Meylaerts SA

Summary



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